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31 December 2023 | ARTICLE
Prevalence of SARS-CoV-2 antibodies among Belgian nursing home residents and staff during the primary COVID-19 vaccination campaign
BACKGROUND: Nursing home residents (NHR) and staff have been disproportionally affected by the COVID-19 pandemic and were therefore prioritised in the COVID-19 vaccination strategy. However, frail older adults, like NHR, are known to have decrease...
Auteurs: Eline Meyers, Liselore De Rop, Ellen Deschepper, Els Duysburgh, Tine De Burghgraeve, Pauline Van Ngoc, Marina Digregorio, Simon Delogne, Anja Coen, Nele De Clercq, Laetitia Buret, Samuel Coenen, An De Sutter, Beatrice Scholtes, Jan Y Verbakel, Piet Cools en Stefan Heytens
31 December 2023 | ARTICLE
Initial symptoms and three months follow-up after acute COVID-19 in outpatients: An international prospective cohort study
BACKGROUND: Most studies on long-term follow-up of patients with COVID-19 focused on hospitalised patients. No prospective study with structured follow-up has been performed in non-hospitalised patients with COVID-19. OBJECTIVES: To assess long-CO...
Auteurs: Katarina Hedin, Alike W van der Velden, Malene Plejdrup Hansen, Anna B Moberg, Anca Balan, Pascale Bruno, Samuel Coenen, Eskild Johansen, Anna Kowalczyk, Peter Konstantin Kurotschka, Sanne R van der Linde, Lile Malania, Jorn Rohde, Jan Verbakel, Heike Vornhagen en Akke Vellinga
31 December 2023 | ARTICLE
Clinical pathway of COVID-19 patients in primary health care in 30 European countries: Eurodata study
BACKGROUND: Most COVID-19 patients were treated in primary health care (PHC) in Europe. OBJECTIVES: To demonstrate the scope of PHC workflow during the COVID-19 pandemic emphasising similarities and differences of patient's clinical pathways in Eu...
Auteurs: Sara Ares-Blanco, Marina Guisado-Clavero, Lourdes Ramos Del Rio, Ileana Gefaell Larrondo, Louise Fitzgerald, Limor Adler, Radost Assenova, Maria Bakola, Sabine Bayen, Elena Brutskaya-Stempkovskaya, Iliana-Carmen Busneag, Philippe-Richard Domeyer, Dragan Gjorgjievski, Kathryn Hoffmann, Oksana Ilkov, Vasilis Trifon Karathanos, Aleksandar Kirkovski, Snezana Knezevic, Buesra Cimen Korkmaz, Bruno Heleno, Katarzyna Nessler, Liubove Murauskiene, Ana Luisa Neves, Naldy Parodi Lopez, Abel Perjes, Davorina Petek, Ferdinando Petrazzuoli, Goranka Petricek, Bohumil Seifert, Alicia Serafini, Theresa Sentker, Paula Tiili, Peter Torzsa, Bert Vaes, Gijs van Pottebergh, Shlomo Vinker, Maria Pilar Astier-Pena, Raquel Gomez-Bravo en Heidrun Lingner
Auteurs: Arne Janssens, bert Vaes, Chloé Abels, Jonas Crèvecoeur, Pavlos Mamouris, Barbara Merckx, Pieter Libin, Gijs Van Pottelbergh en Thomas Neyens
5 September 2023 | ARTICLE
Authors' reply.
Auteurs: Ann-Sophie Page, Jan Y Verbakel en Jan Deprest
1 September 2023 | ARTICLE
Characteristics of self-management support (SMS) interventions and their impact on Quality of Life (QoL) in adults with chronic diseases: An umbrella review of systematic reviews
OBJECTIVE: To provide an overview of types and characteristics of self-management support (SMS) interventions in adults with chronic disease and to assess the impact on the patient reported outcome Quality of Life (QoL). METHODS: An umbrella revie...
Auteurs: Lotte Timmermans, Elena Golder, Peter Decat, Veerle Foulon, Ann Van Hecke en Birgitte Schoenmakers
1 September 2023 | ARTICLE
Communities of practice in residential aged care: A rapid review
BACKGROUND: Communities of practice (CoPs) have the potential to help address the residential aged care system's need for continuing education and quality improvement. CoPs have been used in healthcare to improve clinical practice; however, little...
Auteurs: Martin Read, Sanne Peters, Noleen Bennett, Jill J Francis, Deirdre Fetherstonhaugh, Wen Kwang Lim en Joanne Tropea
Auteurs: Laure Sillis, Cleo Vandegoor, Cato Vercaeren, Karel Allegaert, Annick Bogaerts, Maarten De Vos, Titia Hompes, Anne Smits, Kristel Van Calsteren, Jan Verbakel, Veerle Foulon en Michael Ceulemans
31 August 2023 | ARTICLE
Cost-effectiveness of adding ezetimibe and/or PCSK9 inhibitors to high-dose statins for secondary prevention of cardiovascular disease in Chinese adults.
OBJECTIVES: The latest international guideline recommended the add-on therapy of ezetimibe and PCSK9 inhibitors in selected people for the secondary prevention of cardiovascular diseases (CVDs). However, it remains unclear whether these regimens f...
Auteurs: Yuliang Xiang, Lei Gan, Heyue Du, Qiukui Hao, Bert Aertgeerts, Sheyu Li en Ming Hu
30 August 2023 | ARTICLE
Development and content of a community-based reablement programme (I-MANAGE): a co-creation study
OBJECTIVES: As age increases, people generally start experiencing problems related to independent living, resulting in an increased need for long-term care services. Investing in sustainable solutions to promote independent living is therefore ess...
Auteurs: Ines Mouchaers, Silke Metzelthin, Jolanda van Haastregt, Ellen Vlaeyen, Geert Goderis en Hilde Verbeek
Auteurs: Vasiliki Andreou, Sanne Peters, Jan Eggermont en Birgitte Schoenmakers
22 August 2023 | ARTICLE
Implementation and evaluation of a complex intervention to improve information availability at the interface between inpatient and outpatient care in older patients with multimorbidity and polypharmacy (HYPERION-TransCare) - study protocol for a pilot and feasibility cluster-randomized controlled trial in general practice in Germany
BACKGROUND: Despite attempts to improve the cross-sectoral flow of information, difficulties remain in routine healthcare. The resulting negative impact on continuity of care is often associated with poor health outcomes, especially in older patie...
Auteurs: Astrid-Alexandra Klein, Jenny Petermann, Franziska Brosse, Steve Piller, Martin Kramer, Maria Hanf, Truc Sophia Dinh, Sylvia Schulz-Rothe, Jennifer Engler, Karola Mergenthal, Hanna M Seidling, Sophia Klasing, Nina Timmesfeld, Marjan van den Akker en Karen Voigt
11 August 2023 | ARTICLE
The willingness and barriers to collaborate in the care of frail older adults: perspectives of primary care professionals
BACKGROUND: This study investigated the perspectives of primary care professionals, in particular general practitioners, registered nurses, physiotherapists and occupational therapists, on inter-professional collaboration, the barriers and the fac...
Auteurs: Leen De Coninck, Anja Declercq, Leen Bouckaert, Carola Dopp, Maud JL Graff en Bert Aertgeerts
29 July 2023 | ARTICLE
Best practice guidance for antibiotic audit and feedback interventions in primary care: a modified Delphi study from the Joint Programming Initiative on Antimicrobial resistance: Primary Care Antibiotic Audit and Feedback Network (JPIAMR-PAAN)
BACKGROUND: Primary care is a critical partner for antimicrobial stewardship efforts given its high human antibiotic usage. Peer comparison audit and feedback (A&F) is often used to reduce inappropriate antibiotic prescribing. The design and imple...
Auteurs: Kevin LL Schwartz, Alice XT Xu, Sarah Alderson, Lars Bjerrum, Jamie Brehaut, Benjamin CC Brown, Heiner CC Bucher, An De Sutter, Nick Francis, Jeremy Grimshaw, Ronny Gunnarsson, Sigurd Hoye, Noah Ivers, Donna MM Lecky, Morten Lindbaek, Jeffrey AA Linder, Paul Little, Benedikte Olsen Michalsen, Denise O'Connor, Celine Pulcini, Par-Daniel Sundvall, Pia Touboul Lundgren, Jan YY Verbakel en Theo JJ Verheij
15 July 2023 | OTHER
Diagnostic and Prognostic research: bench to bedside and beyond
Basics of RCTs and diagnostic and prognostic research
Auteurs: Jan Verbakel
14 July 2023 | ARTICLE
Predictors for unplanned hospital admissions in community dwelling adults: A dynamic cohort study.
BACKGROUND: Polypharmacy and inappropriate medication use are associated with unplanned hospital admissions. Targeted interventions might reduce the hospitalization risk. Yet, it remains unclear which patient profiles derive the largest benefit fr...
Auteurs: Julie Hias, Laura Hellemans, Shauni Nuyts, Bert Vaes, Xavier Rygaert, Jos Tournoy en Lorenz Van der Linden
13 July 2023 | OTHER
Genetische factoren bepalen mee je risico op long covid: "De puzzelstukjes vallen stilaan in elkaar"
Wetenschappers hebben een genetische variant ontdekt die gelinkt is aan long covid, een chronische aandoening die ontstaat na een covidinfectie. Dat blijkt uit nieuw onderzoek, gepubliceerd op de website MedRxiv. Mensen met long covid hebben vaker...
Auteurs: Jan Verbakel en Peter Brems
4 July 2023 | ARTICLE
Trends in oral anticoagulant prescription in patients with nonvalvular atrial fibrillation in Flanders and the impact of switching patients from vitamin K antagonists to DOACS in terms of the burden caused by complications of the disease: a registry-based study
CONTEXT: Since the introduction of direct oral anticoagulants (DOACs) for the treatment of nonvalvular atrial fibrillation (Afib), oral anticoagulants (OACs) prescription has evolved. AIM: We aim first to explore the OACs prescription behaviour in...
Auteurs: Elvire Nakhoul, Bert Vaes, Pavlos Mamouris en Jean-Marie Degryse
3 July 2023 | ARTICLE
Patients' experiences and expectations of the General Practitioner's role during bereavement care after losing a loved one: A qualitative study
General practitioners (GPs) are well positioned to support patients during their grieving process. This study investigated patients' experiences and expectations of their GP's role during bereavement care after losing a loved one. Semi-structured ...
Auteurs: Julie Van Goethem, Marie Verschaeve, Sanne Peters en Miek Smeets
21 June 2023 | ARTICLE
Clinical effectiveness of rehabilitation in ambulatory care for patients with persisting symptoms after COVID-19: a systematic review.
BACKGROUND: Lingering symptoms after acute COVID-19 present a major challenge to ambulatory care services. Since there are reservations regarding their optimal management, we aimed to collate all available evidence on the effects of rehabilitation...
Auteurs: Hannelore Dillen, geertruida Bekkering, Sofie Gijsbers, Yannick Vande Weygaerde, Maarten Van Herck, Sarah Haesevoets, David AG Bos, Ann Li, Wim Janssens, Henricus Gosselink, Thierry Troosters en Jan Y Verbakel
20 June 2023 | ARTICLE
Population health management in Belgium: a call-to-action and case study
BACKGROUND: Although there are already success stories, population health management in Belgium is still in its infancy. A health system transformation approach such as population health management may be suited to address the public health issue ...
Auteurs: Betty Steenkamer, Bert Vaes, Ernst Rietzschel, John Crombez, Sabina De Geest, Fabian Demeure, Marijke Gielen, Michel P Hermans, Stefan Teughels, Peter Vanacker, Thierry van der Schueren en Steven Simoens
14 June 2023 | ARTICLE
Community pharmacists' perceptions on multidisciplinary heart failure care: an exploratory qualitative study
BACKGROUND: Heart failure (HF) is an important health problem and guidelines recommend multidisciplinary management. The pharmacist is an important member of the multidisciplinary heart failure team, both in the hospital and community setting. Thi...
Auteurs: Willem Raat, Pauline Truyts, Justine Gaillaert, Marie Van de Putte, Lorenz Van der Linden, Stefan Janssens, Bert Vaes en Miek Smeets
Auteurs: Mieke Embo, Olivia De Ruyck, Jessica Morton, Sofie Van Ostaeyen, Clara Wasiak, Marieke Robbrecht, Vasiliki Andreou, Oona Janssens, Helena Demey en Martin Valcke
10 June 2023 | ARTICLE
Do the lockdown-imposed changes in a wastewater treatment plant catchment's socio-demographics impact longitudinal temporal trends in psychoactive pharmaceutical use?
Wastewater-based epidemiology (WBE) includes the analysis of human metabolic biomarkers of xenobiotics in influent wastewater. WBE complements existing drug utilization approaches and provides objective, spatio-temporal information on the consumpt...
Auteurs: Tim Boogaerts, Maarten Quireyns, Hans De Loof, Xander Bertels, Natan Van Wichelen, Bram Pussig, Jan Saevels, Lies Lahousse, Pauline Bonmariage, Wouter Hamelinck, Bert Aertgeerts, Adrian Covaci en Alexander LN van Nuijs
Auteurs: Ruben Burvenich, Stefan Heytens, David Bos, An De Sutter, Thomas Struyf en Jan Verbakel
Auteurs: Hannelore Dillen, Daan Pauwels, Daniëlle Snijders, Jo Wouters, Laure Wynants en Jan Y Verbakel
Auteurs: Erinn D'hulster, Tine De Burghgraeve, Jeroen Luyten en Jan Verbakel
8 June 2023 | OTHER
Accuracy of routine laboratory tests to predict mortality and deterioration to severe or critical COVID-19 in people with SARS-CoV-2
Background: Estimating the risk of severe outcomes for SARS-CoV-2 patients can help prioritise medical care. Questions: Can routine blood-based laboratory tests help predict mortality and deterioration from mild/moderate to severe/critical COVID-1...
Auteurs: Liselore De Rop, Inge Stegeman, Gea Holtman, Rene Spijker, Mariska Leeflang, David Bos, Jenifer Otieno, Fade Alkhlaileh, Eleanor Ochodo en Jan Verbakel