Publicaties

Een overzicht van alle publicaties van de onderzoekers bij ACHG
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8 November 2022 | DISSERTATION
Diagnosing Urinary Tract Infections in children. Value of signs, symptoms, and point-of-care tests in primary care.
Introduction Urinary tract Infections (UTIs) occur in 1 of 20 children presenting to general practice. Diagnosis is challenging because the signs and symptoms of UTI in children are non-specific. Ruling out UTI requires urine culture, however thes...
Auteurs: Hanne Boon
Auteurs: Laure Sillis, Veerle Foulon, Karel Allegaert, Annick Bogaerts, Maarten De Vos, Titia Hompes, Anne Smits, Kristel Van Calsteren, Jan Verbakel en Michael Ceulemans
22 July 2022 | ARTICLE
Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection.
BACKGROUND: Accurate rapid diagnostic tests for SARS-CoV-2 infection would be a useful tool to help manage the COVID-19 pandemic. Testing strategies that use rapid antigen tests to detect current infection have the potential to increase access to ...
Auteurs: Jacqueline Dinnes, Pawana Sharma, Sarah Berhane, Susanna S van Wyk, Nicholas Nyaaba, Julie Domen, Melissa Taylor, Jane Cunningham, Clare Davenport, Sabine Dittrich, Devy Emperador, Lotty Hooft, Mariska Mg Leeflang, Matthew Df McInnes, René Spijker, Jan Y Verbakel, Yemisi Takwoingi, Sian Taylor-Phillips, Ann Van den Bruel, Jonathan J Deeks en Cochrane COVID-19 Diagnostic Test Accuracy Group
20 July 2022 | ARTICLE
Incidence rates and trends of childhood urinary tract infections and antibiotic prescribing: registry-based study in general practices (2000 to 2020).
BACKGROUND: To improve the management of childhood urinary tract infections, it is essential to understand the incidence rates, testing and treatment strategy. METHODS: A retrospective study using data from 45 to 104 general practices (2000 to 202...
Auteurs: Hanne A Boon, Thomas Struyf, Jonas Crèvecoeur, Nicolas Delvaux, Gijs Van Pottelbergh, Bert Vaes, Ann Van den Bruel en Jan Y Verbakel
14 July 2022 | ARTICLE
Study protocol for a randomised controlled trial on the use of intraoperative ultrasound-guided laparoscopic ovarian cystectomy (UGLOC) as a method of fertility preservation in the management of benign ovarian cysts.
INTRODUCTION: The lifetime risk of women undergoing surgery for the presence of benign ovarian pathology in the UK is 5%-10%. Despite minimally invasive surgical techniques, evidence suggests a number of healthy ovarian follicles and tissues are r...
Auteurs: Lorraine S Kasaven, Benjamin P Jones, Sadaf Ghaem-Maghami, Jan Yvan Jos Verbakel, Mona El-Bahrawy, Srdjan Saso en Joseph Yazbek
7 July 2022 | ARTICLE
Stakeholder Perspectives on the Development and Implementation of a Polypharmacy Management Program in Germany: Results of a Qualitative Study.
Structured management programs have been developed for single diseases but rarely for patients with multiple medications. We conducted a qualitative study to investigate the views of stakeholders on the development and implementation of a polyphar...
Auteurs: Truc Sophia Dinh, Maria-Sophie Brueckle, Ana Isabel González-González, Julian Witte, Marjan van den Akker, Ferdinand M Gerlach, Christiane Muth en On Behalf Of The Evita Study Group
28 June 2022 | ARTICLE
Trends in the epidemiology of depression and comorbidities from 2000 to 2019 in Belgium.
BACKGROUND: Depression is a common mental disorder in family practice with an impact on global health. The aim of this study is to provide insight in the trends of epidemiological measures as well as pharmacological treatments and comorbidities of...
Auteurs: Roosje Walrave, Simon Gabriël Beerten, Pavlos Mamouris, Kristien Coteur, Marc Van Nuland, Gijs Van Pottelbergh, Lidia Casas en Bert Vaes
Auteurs: Laure Sillis, Veerle Foulon, Karel Allegaert, Annick Bogaerts, Maarten De Vos, Titia Hompes, Anne Smits, Kristel Van Calsteren, Jan Verbakel en Michael Ceulemans
22 June 2022 | ARTICLE
Effect of COVID-19 Vaccination Campaign in Belgian Nursing Homes on COVID-19 Cases, Hospital Admissions, and Deaths among Residents.
In view of the grave situation during the first two waves of SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus-2), nursing homes (NHs) were prioritised for vaccination once vaccines became available in Belgium. The aim of this study ...
Auteurs: Sara Dequeker, Milena Callies, Catharina Vernemmen, Katrien Latour, Laura Int Panis, Romain Mahieu, Lennert Noppe, Muhammet Savsin en Els Duysburgh
17 June 2022 | ARTICLE
Use of an Electronic Medication Management Support System in Patients with Polypharmacy in General Practice: A Quantitative Process Evaluation of the AdAM Trial.
Polypharmacy is associated with a risk of negative health outcomes. Potentially inappropriate medications, interactions resulting from contradicting medical guidelines, and inappropriate monitoring, all increase the risk. This process evaluation (...
Auteurs: Robin Brünn, Dorothea Lemke, Jale Basten, Petra Kellermann-Mühlhoff, Juliane Köberlein-Neu, Christiane Muth, Marjan van den Akker en On Behalf Of The AdAM Study Group
Auteurs: Chantal Van Audenhove
Auteurs: Chantal Van Audenhove
13 June 2022 | ARTICLE
Chronic nonbacterial osteomyelitis in children: a multicentre Belgian cohort of 30 children.
BACKGROUND: To evaluate clinical characteristics, imaging findings, therapeutic approach and outcome of paediatric patients with Chronic Non-Bacterial Osteomyelitis (CNO). METHODS: Retrospective review of 30 children diagnosed with CNO at two tert...
Auteurs: Sara Kaut, Ine Van den Wyngaert, Davy Christiaens, Carine Wouters, Nathalie Noppe, Nele Herregods, Joke Dehoorne en Lien De Somer
7 June 2022 | ARTICLE
The guided use of an e-health tool to strengthen health literacy. A pilot study in a multicultural diabetes population in a primary care clinic in Brussels
Objectives: We aimed to investigate whether the use of an e-health tool, guided by a healthcare provider, can improve health literacy (HL) in primary care. Methods: We set up a longitudinal prospective cohort study in a primary care clinic in Brus...
Auteurs: Lien Mertens en Bert (Supervision) Aertgeerts
1 June 2022 | ARTICLE
New clinical prediction model for early recognition of sepsis in adult primary care patients: a prospective diagnostic cohort study of development and external validation.
BACKGROUND: Recognising patients who need immediate hospital treatment for sepsis while simultaneously limiting unnecessary referrals is challenging for GPs. AIM: To develop and validate a sepsis prediction model for adult patients in primary care...
Auteurs: Feike J Loots, Marleen Smits, Rogier M Hopstaken, Kevin Jenniskens, Fleur H Schroeten, Ann van den Bruel, Alma C van de Pol, Jan Jelrik Oosterheert, Hjalmar Bouma, Paul Little, Michael Moore, Sanne van Delft, Douwe Rijpsma, Joris Holkenborg, Bas Ct van Bussel, Ralph Laven, Dennis Cjj Bergmans, Jacobien J Hoogerwerf, Gideon Hp Latten, Eefje Gpm de Bont, Paul Giesen, Annemarie den Harder, Ron Kusters, Arthur Rh van Zanten en Theo Jm Verheij
26 May 2022 | BOOK CHAPTER
An Empowering Dementia Environment
Auteurs: Jos Tournoy, John Keady, Mythily Subramaniam, Aline Sevenants, Chantal Van Audenhove, Iris Van Steenwinkel, Ann Heylighen en Maarten Van Den Bossche
20 May 2022 | OTHER
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19.
BACKGROUND: COVID-19 illness is highly variable, ranging from infection with no symptoms through to pneumonia and life-threatening consequences. Symptoms such as fever, cough, or loss of sense of smell (anosmia) or taste (ageusia), can help flag e...
Auteurs: Thomas Struyf, Jonathan J Deeks, Jacqueline Dinnes, Yemisi Takwoingi, Clare Davenport, Mariska Mg Leeflang, René Spijker, Lotty Hooft, Devy Emperador, Julie Domen, Anouk Tans, Stéphanie Janssens, Dakshitha Wickramasinghe, Viktor Lannoy, Sebastiaan RA Horn, Ann Van den Bruel en Cochrane COVID-19 Diagnostic Test Accuracy Group
Auteurs: Ruben Burvenich en Hannelore Dillen
Auteurs: Chantal Van Audenhove
16 May 2022 | ARTICLE
Thoracic imaging tests for the diagnosis of COVID-19.
BACKGROUND: Our March 2021 edition of this review showed thoracic imaging computed tomography (CT) to be sensitive and moderately specific in diagnosing COVID-19 pneumonia. This new edition is an update of the review. OBJECTIVES: Our objectives we...
Auteurs: Sanam Ebrahimzadeh, Nayaar Islam, Haben Dawit, Jean-Paul Salameh, Sakib Kazi, Nicholas Fabiano, Lee Treanor, Marissa Absi, Faraz Ahmad, Paul Rooprai, Ahmed Al Khalil, Kelly Harper, Neil Kamra, Mariska Mg Leeflang, Lotty Hooft, Christian B van der Pol, Ross Prager, Samanjit S Hare, Carole Dennie, René Spijker, Jonathan J Deeks, Jacqueline Dinnes, Kevin Jenniskens, Daniël A Korevaar, Jérémie F Cohen, Ann Van den Bruel, Yemisi Takwoingi, Janneke van de Wijgert, Junfeng Wang, Elena Pena, Sandra Sabongui, Matthew Df McInnes en Cochrane COVID-19 Diagnostic Test Accuracy Group
Auteurs: Hanne Van Horebeek, Kathleen De Cuyper, Anja Declercq en Chantal Van Audenhove
10 May 2022 | ARTICLE
GPs’ perspectives on diagnosing childhood urinary tract infections: a qualitative study
BACKGROUND: Diagnosis and management of childhood urinary tract infection (UTI) is challenging in general practice because of a range of factors. AIM: To explore GPs' perspectives concerning the barriers to and facilitators for diagnosis and manag...
Auteurs: Hanne Boon, Ann Van den Bruel en Jan Verbakel
4 May 2022 | ARTICLE
Safety of proprotein convertase subtilisin/kexin 9 inhibitors: a systematic review and meta-analysis
OBJECTIVE: To determine the harms of proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors in people who need lipid-lowering therapy. METHODS: This systematic review included randomised controlled trials that compared PCSK9 inhibitors with p...
Auteurs: Jing Li, Heyue Du, Yang Wang, Bert Aertgeerts, Gordon Guyatt, Qiukui Hao, Yanjiao Shen, Ling Li, Na Su, Nicolas Delvaux, Geertruida Bekkering, Safi U Khan, Irbaz B Riaz, Per Olav Vandvik, Baihai Su, Haoming Tian en Sheyu Li
4 May 2022 | ARTICLE
PCSK9 inhibitors and ezetimibe with or without statin therapy for cardiovascular risk reduction: a systematic review and network meta-analysis.
OBJECTIVE: To compare the impact of ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on cardiovascular outcomes in adults taking maximally tolerated statin therapy or who are statin intolerant. DESIGN: Network meta-an...
Auteurs: Safi U Khan, Siva H Yedlapati, Ahmad N Lone, Qiukui Hao, Gordon Guyatt, Nicolas Delvaux, Geertruida E Trudy Bekkering, Per Olav Vandvik, Irbaz Bin Riaz, Sheyu Li, Bert Aertgeerts en Nicolas Rodondi
Auteurs: Dominique Liesse
1 May 2022 | ARTICLE
What do we know about written assessment of health professionals' communication skills? A scoping review.
OBJECTIVE: The aim of this scoping review was to investigate the published literature on written assessment of communication skills in health professionals' education. METHODS: Pubmed, Embase, Cinahl and Psychnfo were screened for the period 1/199...
Auteurs: Noelle Junod Perron, Peter Pype, Marc van Nuland, Maria Magdalena Bujnowska-Fedak, Marcela Dohms, Geurt Essers, Ragnar Joakimsen, Zoi Tsimtsiou en Claudia Kiessling
1 May 2022 | ARTICLE
The Risk of Endometrial Malignancy and Other Endometrial Pathology in Women with Abnormal Uterine Bleeding: An Ultrasound-Based Model Development Study by the IETA Group
OBJECTIVES: The aim of this study was to develop a model that can discriminate between different etiologies of abnormal uterine bleeding. DESIGN: The International Endometrial Tumor Analysis 1 study is a multicenter observational diagnostic study ...
Auteurs: Laure Wynants, Jan Yvan Jos Verbakel, Lil Valentin, Bavo De Cock, M Angela Pascual, Francesco PG Leone, Povilas Sladkevicius, Ruben Heremans, Juan Luis Alcazar, Angelo Votino, Robert Fruscio, Elisabeth Epstein, Tom Bourne, Ben Van Calster, Dirk Timmerman en Thierry Van den Bosch
1 May 2022 | ARTICLE
Lower persistence of anti-nucleocapsid compared to anti-spike antibodies up to one year after SARS-CoV-2 infection.
We retrospectively compared the long-term evolution of IgG anti-spike (S) and anti-nucleocapsid (N) levels (Abbott immunoassays) in 116 non-severe and 115 severe SARS-CoV-2 infected patients from 2 university hospitals up to 365 days post positive...
Auteurs: Jan Van Elslande, Matthijs Oyaert, Natalie Lorent, Yannick Vande Weygaerde, Gijs Van Pottelbergh, Lode Godderis, Marc Van Ranst, Emmanuel André, Elizaveta Padalko, Katrien Lagrou, Stien Vandendriessche en Pieter Vermeersch