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4 April 2022 | ARTICLE
Temporal monitoring of stimulants during the COVID-19 pandemic in Belgium through the analysis of influent wastewater
BACKGROUND AND AIMS: Wastewater-based epidemiology (WBE) is a complementary epidemiological data source to monitor stimulant consumption. The aims were to: (i) study intra- and inter-year temporal changes in stimulant use in Belgium during the fir...
Auteurs: Tim Boogaerts, Maarten Quireyns, Maarten De Prins, Bram Pussig, Hans De Loof, Catharina Matheï, Bert Aertgeerts, Virginie Van Coppenolle, Erik Fransen, Adrian Covaci en Alexander LN Van Nuijs
2 April 2022 | ARTICLE
Experiences and perspectives of marketing authorisation holders towards medication safety monitoring during pregnancy: a pan-European qualitative analysis
Although marketing authorisation holders (MAHs) are involved in monitoring medication safety, it was unclear how they experience their role and current monitoring activities in pregnancy. Therefore, a qualitative study using online focus groups wi...
Auteurs: Laure (Conceptualization Sillis, Veerle (Conceptualization Foulon, Jan (Conceptualization Verbakel en Michael (Conceptualization Ceulemans
1 April 2022 | ARTICLE
Trends in guideline implementation: an updated scoping review protocol.
OBJECTIVE: The objective of this review is to assess trends in guideline implementation, including the interventions used, rationale provided, and the impact on patient or health care professional knowledge, behavior or outcomes. INTRODUCTION: Gui...
Auteurs: Anna R Gagliardi, Jennifer Malinowski, Zachary Munn, Sanne Peters en Emily Senerth
1 April 2022 | ARTICLE
IgG anti-spike antibody levels in healthcare workers with and without prior COVID-19 up to 3 months after BNT162b2 vaccination.
We report IgG anti-spike levels up to 3 months after vaccination with 2 doses of BNT162b2 mRNA vaccine in healthcare workers (HCW). The antibody response was significantly stronger in previously infected vaccinated HCW compared to uninfected HCW, ...
Auteurs: Jan Van Elslande, Matthias Weemaes, Lode Godderis, Gijs Van Pottelbergh, Xavier Bossuyt en Pieter Vermeersch
1 April 2022 | ARTICLE
Development of an intervention to improve informational continuity of care in older patients with polypharmacy at the interface between general practice and hospital care: protocol for a participatory qualitative study in Germany
INTRODUCTION: Older patients with multimorbidity, polypharmacy and related complex care needs represent a growing proportion of the population and a challenge for healthcare systems. Particularly in transitional care (hospital admission and hospit...
Auteurs: Maria-Sophie Brueckle, Truc Sophia Dinh, Astrid-Alexandra Klein, Lisa Rietschel, Jenny Petermann, Franziska Brosse, Sylvia Schulz-Rothe, Ana Isabel Gonzalez-Gonzalez, Martin Kramer, Jennifer Engler, Karola Mergenthal, Christiane Muth, Karen Voigt en Marjan van den Akker
1 April 2022 | ARTICLE
Vaccine Hesitancy towards the COVID-19 Vaccine in a Random National Sample of Belgian Nursing Home Staff Members
In Belgium, nursing home staff (NHS) and residents were prioritised for COVID-19 vaccination. However, vaccine hesitancy may have impacted vaccination rates. In this study, a random stratified sample of NHS (N = 1142), vaccinated and unvaccinated,...
Auteurs: Marina Digregorio, Pauline Van Ngoc, Simon Delogne, Eline Meyers, Ellen Deschepper, Els Duysburgh, Liselore De Rop, Tine De Burghgraeve, Anja Coen, Nele De Clercq, An De Sutter, Jan Y Verbakel, Piet Cools, Stefan Heytens, Laetitia Buret en Beatrice Scholtes
1 April 2022 | ARTICLE
Effectiveness of guided and unguided online alcohol help: A real-life study
Aims: Online interventions reduce the treatment gap between the number of people with alcohol misuse and people who actually receive help. This study investigated the effectiveness and predictors of success of a Belgian online help programme. Meth...
Auteurs: Ans Vangrunderbeek, Ann Raveel, Catharina Mathei, Herwig Claeys, Bert Aertgeerts en Geertruida Bekkering
1 April 2022 | ARTICLE
Downstream activities after laboratory testing in primary care: an exploratory outcome of the ELMO cluster randomised trial (Electronic Laboratory Medicine Ordering with evidence-based order sets in primary care)
OBJECTIVE: To estimate the rate and type of downstream activities (DAs) after laboratory testing in primary care, with a specific focus on check-up laboratory panels, and to explore the effect of a clinical decision support system (CDSS) for labor...
Auteurs: Veerle Piessens, Nicolas Delvaux, Stefan Heytens, Bert Aertgeerts en An De Sutter
31 March 2022 | ARTICLE
Self-management support in flemish primary care practice: the development of a preliminary conceptual model using a qualitative approach
BACKGROUND: Coping with a chronic disease can be really challenging. Self-management represents a promising strategy to improve daily life experiences. The role of primary healthcare professionals cannot be underestimated in supporting self-manage...
Auteurs: Lotte Timmermans, Dagje Boeykens, Mustafa Muhammed Sirimsi, Peter Decat, Veerle Foulon, Ann Van Hecke, Mieke Vermandere en Birgitte Schoenmakers
25 March 2022 | ARTICLE
Recommendations for Researchers on Synchronous, Online, Nominal Group Sessions in Times of COVID-19: Fishbone Analysis.
BACKGROUND: In times of COVID-19, we are challenged to experiment with alternative platforms or software to connect people. In particular, the struggle that arose in health research was how to interact with patients and care professionals. The lat...
Auteurs: Lotte Timmermans, Ine Huybrechts, Peter Decat, Veerle Foulon, Ann Van Hecke, Mieke Vermandere en Birgitte Schoenmakers
Auteurs: Erinn D'hulster, Charlotte Quintens, Raf Bisschops, Rik Willems, Willy E Peetermans, Jan Y Verbakel en Jeroen Luyten
18 March 2022 | ARTICLE
Development of primary care quality indicators for chronic obstructive pulmonary disease using a Delphi-derived method
High-quality care for patients with COPD is necessary. To achieve quality improvement in primary care, the general practitioner and the electronic health record (EHR) play an important role. The aim of this study was to develop a set of evidence-b...
Auteurs: Sigrid Dewaele, Steve Van den Bulck, Lien Gerne en Bert Vaes
17 March 2022 | OTHER
Both medical and context elements influence the decision making processes of pediatricians
We wanted to investigate the relationship of medical and non-medical factors with the clinical decision-making of pediatricians. We hypothesize that the addition of relevant medical information (either alarming or reassuring) will influence the ph...
Auteurs: Lisa Schurmans, David De Coninck, Birgitte Schoenmakers, Peter de Winter en Jaan Toelen
11 March 2022 | ARTICLE
Trapped in a double cage: How patients’ partners experience the diagnosis of advanced cancer in times of the COVID-19 pandemic: An interpretative phenomenological analysis
Background: When confronting a partner’s diagnosis of advanced cancer, family caregivers are often protected against severe psychological illness by their mental resilience. However, the current COVID-19 pandemic endangers this resilience through ...
Auteurs: Sophie Opsomer, Sofie Joossens, Jan De Lepeleire, Peter Pype en Emelien Lauwerier
Auteurs: Hannelore Dillen, Ruben Burvenich, Tine De Burghgraeve en Jan Y Verbakel
Auteurs: Lisa Schurmans, David De Coninck, Birgitte Schoenmakers, Peter de Winter en Jaan Toelen
Auteurs: David Bos, Tine De Burghgraeve, Marieke Lemiengre, An De Sutter, Frank Buntinx en Jan Verbakel
10 March 2022 | OTHER
Accepted abstract and poster presentation at the 4th National Point of Care Testing Symposium.
Auteurs: Liselore De Rop, Tine De Burghgraeve, Marieke Lemiengre, An De Sutter, Frank Buntinx en Jan Verbakel
7 March 2022 | ARTICLE
A Resampling Method to Improve the Prognostic Model of End-Stage Kidney Disease: A Better Strategy for Imbalanced Data
Background: Prognostic models can help to identify patients at risk for end-stage kidney disease (ESKD) at an earlier stage to provide preventive medical interventions. Previous studies mostly applied the Cox proportional hazards model. The aim of...
Auteurs: Xi Shi, Tingyu Qu, Gijs Van Pottelbergh, Marjan van den Akker en Bart De Moor
4 March 2022 | ARTICLE
Organisation and quality monitoring for point-of-care testing (POCT) in Belgium: proposal for an expansion of the legal framework for POCT into primary health care
BACKGROUND: There is a trend towards decentralisation of laboratory tests by means of Point-of-Care testing (POCT). Within hospitals, Belgian law requires a POCT policy, coordinated by the clinical laboratory. There is however no legal framework f...
Auteurs: Viviane Van Hoof, Dragos Barglazan, Laurent Blairon, Bob Braekevelt, Regis Debois, Nathalie Veronique J De Vos, Damien Gruson, Jef Jonckheere, Katrien Lanckmans, Marc Moens, Bart Peeters, Joris Penders, Alain Roman, Lieve Van Hoovels, Florent Vanstapel, Jan Y Verbakel, Ann Verdonck en Alain G Verstraete
Auteurs: Ines Mouchaers, Hilde Verbeek, Gertrudis IJM Kempen, Jolanda CM van Haastregt, Ellen Vlaeyen, Geert Goderis en Silke F Metzelthin
Auteurs: Ruben Burvenich, Gertruida Bekkering en Patrik Vankrunkelsven
1 March 2022 | ARTICLE
MRSA surveillance programmes worldwide: moving towards a harmonised international approach
Multinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national structures for data collection. This study aimed to capture the diversity of national MRSA surveillance programmes and to propos...
Auteurs: Valerie O Baede, Michael Z David, Arjana Tambic Andrasevic, Dominique S Blanc, Michael Borg, Grainne Brennan, Boudewijn Catry, Aurelie Chabaud, Joanna Empel, Hege Enger, Marie Hallin, Marina Ivanova, Andreas Kronenberg, Kuntaman Kuntaman, Anders Rhod Larsen, Katrien Latour, Jodi A Lindsay, Bruno Pichon, Dewi Santosaningsih, Leo M Schouls, Francois Vandenesch, Guido Werner, Dorota Zabicka, Helena Zemlickova, Harald Seifert en Margreet C Vos
25 February 2022 | ARTICLE
Fifteen-year trajectories of multimorbidity and polypharmacy in Dutch primary care-A longitudinal analysis of age and sex patterns
OBJECTIVE: After stratifying for age, sex and multimorbidity at baseline, our aim is to analyse time trends in incident multimorbidity and polypharmacy in the 15-year clinical trajectories of individual patients in a family medicine setting. METHO...
Auteurs: Rein Vos, Jos Boesten en Marjan van den Akker
Auteurs: Marleen De Coninck, Leen Bouckaert, Evelien Gielen, Koen Milisen, Ellen Vlaeyen, Delphine Despriet, Jan Tessier, Annelies Geeraerts, Leen Verstraeten, Jolien Adriaenssen, Jonas Callens, Janri De Jaegere, Justien Demeulenaere, Vera Deryckere, Reini Haverals, Arwhen Huyghe, Annelien Kerckx, Timothy Moreels, Niels Peeters, Lia Robyns en Daphne Kos
23 February 2022 | ARTICLE
Prevalence and incidence of chemotherapy-induced taste alterations in adult cancer patients: a systematic review protocol.
OBJECTIVE: This study will on will synthesize the available evidence on the prevalence and incidence of chemotherapy-induced taste alterations in adult cancer patients. INTRODUCTION: Taste and smell alterations in cancer patients due to chemothera...
Auteurs: Marleen Corremans, Dimitri Mortelmans, Bart Geurden, Sarah Luyten en Geertruida Bekkering
Auteurs: L Peckeu-Abboud, E van Kleef, T Smekens, K Latour, S Dequeker, L Int Panis en M Laga
22 February 2022 | ARTICLE
Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies
Background: In non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the treatment/exposure group and c...
Auteurs: Lamprini Syrogiannouli, Lea Wildisen, Christiaan Meuwese, Douglas C Bauer, Anne R Cappola, Jacobijn Gussekloo, Wendy PJ den Elzen, Stella Trompet, Rudi GJ Westendorp, J Wouter Jukema, Luigi Ferrucci, Graziano Ceresini, Bjorn O Asvold, Layal Chaker, Robin P Peeters, Misa Imaizumi, Waka Ohishi, Bert Vaes, Henry Voelzke, Jose A Sgarbi, John P Walsh, Robin PF Dullaart, Stephan JL Bakker, Massimo Iacoviello, Nicolas Rodondi en Cinzia Del Giovane