PURPOSE: Persons with Multiple Sclerosis (PwMS) are physically inactive and spend more time in sedentary behaviours than healthy persons, which increases the risk of developing cardiometabolic diseases. In this randomised crossover study, the card...
Auteurs:Ine Nieste, Wouter MA Franssen, Bernard MFM Duvivier, Jan Spaas, Hans HCM Savelberg en Bert O Eijnde
CONTEXT: Since the introduction of direct oral anticoagulants (DOACs) for the treatment of nonvalvular atrial fibrillation (Afib), oral anticoagulants (OACs) prescription has evolved. AIM: We aim first to explore the OACs prescription behaviour in...
Auteurs:Elvire Nakhoul, Bert Vaes, Pavlos Mamouris en Jean-Marie Degryse
Auteurs:Hannelore Dillen, Geertruida Bekkering, Sofie Gijsbers, Yannick Vande Weygaerde, Sarah Haesevoets, Maarten Van Herck, David Bos, Ann Li, Henricus Gosselink, Thierry Troosters en Jan Verbakel
BACKGROUND: Contrary to most European guidelines, benzodiazepine receptor agonists (BZRA) are often used continuously at a low dosage, being the most common form of long-term use. In Belgium, BZRA use is monitored by analyzing self-report data abo...
Auteurs:Kristien Coteur, Pavlos Mamouris, Bert Vaes, Marc Van Nuland, Catharina Mathei en Birgitte Schoenmakers
Auteurs:Lotte Timmermans, Dagje Boeykens, Mustafa Muhammed Sirimsi, Peter Decat, Veerle Foulon, Ann Van Hecke, Mieke Vermandere en Birgitte Schoenmakers
BACKGROUND: In the COVID-19 pandemic, numerous researchers postponed their patient and public involvement (PPI) activities. This was mainly due to assumptions on patients' willingness and skills to participate digitally. In fact, digital PPI works...
Auteurs:Jennifer Engler, Franziska Brosse, Truc Sophia Dinh, Astrid-Alexandra Klein, Maria-Sophie Brueckle, Jenny Petermann, Christiane Muth, Karola Mergenthal, Marjan van den Akker en Karen Voigt
Auteurs:Simon Beerten, Jan Vandamme, jonas Crèvecoeur, steve Van den Bulck, bert Aertgeerts, nicolas Delvaux, gijs Van Pottelbergh, mieke Vermandere, laura Tops, thomas Neyens en bert Vaes
OBJECTIVE: The aim of the present study is to describe a stepwise approach to study which contextual factors might moderate the effect of healthcare interventions and to test feasibility of this approach within the D-SCOPE project. DESIGN: Explora...
Auteurs:Michaël Christiaan John Van der Elst, Birgitte Schoenmakers, Eva Dierckx, Liesbeth De Donder, Ellen De Roeck, Daan Duppen, Bram Fret, Jos MGA Schols, Gertrudis IJM Kempen en Jan De Lepeleire
Auteurs:Lotte Timmermans, Dagje Boeykens, Mustafa Muhammed Sirimsi, Peter Decat, Veerle Foulon, Ann Van Hecke, Mieke Vermandere en Birgitte Schoenmakers
Auteurs:Laure Sillis, Veerle Foulon, Karel Allegaert, Annick Bogaerts, Maarten De Vos, Titia Hompes, Anne Smits, Kristel Van Calsteren, Jan Verbakel en Michael Ceulemans
BACKGROUND: Some autoimmune diseases are associated with an increased risk of cardiovascular disease. We aimed to determine whether or not this is true, and to what extent, for a broad range of autoimmune conditions. METHODS: In this population-ba...
Auteurs:Nathalie Conrad, Geert Verbeke, Geert Molenberghs, Laura Goetschalckx, Thomas Callender, Geraldine Cambridge, Justin C Mason, Kazem Rahimi, John J McMurray en Jan Y Verbakel
General practitioners (GPs) are well positioned to support patients during their grieving process. This study investigated patients' experiences and expectations of their GP's role during bereavement care after losing a loved one. Semi-structured ...
Auteurs:Julie Van Goethem, Marie Verschaeve, Sanne Peters en Miek Smeets
Multimorbidity is of an increasing importance for the health of both children and adults but research has hitherto focused on adult multimorbidity. Hence, public awareness, practice, and policy lack vital information about multimorbidity in childh...
Auteurs:Marjan van den Akker, Mirjam Dieckelmann, Mohammad Akhtar Hussain, Daniela Bond-Smith, Christiane Muth, Sanghamitra Pati, Sonia Saxena, Desiree Silva, Rachel Skoss, Leon Straker, Sandra C Thompson en Judith M Katzenellenbogen
OBJECTIVES: To estimate the prevalence, incidence and longevity of antibodies against SARS-CoV-2 among primary healthcare providers (PHCPs). DESIGN: Prospective cohort study with 12 months of follow-up. SETTING: Primary care in Belgium. PARTICIPAN...
Auteurs:Niels Adriaenssens, Beatrice Scholtes, Robin Bruyndonckx, Pauline Van Ngoc, Jan Y Verbakel, An De Sutter, Stefan Heytens, Ann Van den Bruel, Isabelle Desombere, Pierre Van Damme, Herman Goossens, Laetitia Buret, Els Duysburgh en Samuel Coenen
BACKGROUND AND OBJECTIVES: Four interventions to improve care transitions between hospital and home or community settings for older adults were implemented in Leuven, Belgium over the past four years. These complex interventions consist of multipl...
Auteurs:Amal Fakha, Merel Leithaus, Bram de Boer, Theo van Achterberg, Jan P Hamers en Hilde Verbeek
OBJECTIVE: To determine the harms of proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors in people who need lipid-lowering therapy. METHODS: This systematic review included randomised controlled trials that compared PCSK9 inhibitors with p...
Auteurs:Jing Li, Heyue Du, Yang Wang, Bert Aertgeerts, Gordon Guyatt, Qiukui Hao, Yanjiao Shen, Ling Li, Na Su, Nicolas Delvaux, Geertruida Bekkering, Safi U Khan, Irbaz B Riaz, Per Olav Vandvik, Baihai Su, Haoming Tian en Sheyu Li
OBJECTIVES: To compare opioid prescription rates between patients enrolled in coordinated ambulatory care and patients receiving usual care. DESIGN: In this retrospective cohort study, we analysed claims data for insured patients with non-specific...
Auteurs:Angelina Mueller, Olga Anastasia Amberger, Anastasiya Glushan, Renate Klaassen-Mielke, Claudia Witte, Marjan van den Akker, Robin Bruenn, Ferdinand M Gerlach, Martin Beyer en Kateryna Karimova
INTRODUCTION: Prognosis following surgical rotator cuff repair (RCR) is often established through the assessment of non-modifiable biomedical factors such as tear size. This understates the complex nature of recovery following RCR. There is a need...
Auteurs:Ariane Schwank, Thomas Struyf, Filip Struyf, Paul Blazey, Michel Mertens, David Gisi, Markus Pisan en Mira Meeus
This week I read a press release from the University Hospital of Brussels with the title "30% of hospitalised COVID-19 patients have a heart defect one year after acute illness" [...].
An expert survey was designed to support the development of a workplace-based multi-country intervention tackling depression, anxiety, and mental illness-related stigma in small- and medium-sized enterprises (SMEs). Academic experts and representa...
Auteurs:Bridget Hogg, Ana Moreno-Alcazar, Monika Ditta Toth, Ilinca Serbanescu, Birgit Aust, Caleb Leduc, Charlotte Paterson, Fotini Tsantilla, Kahar Abdulla, Arlinda Cerga-Pashoja, Johanna Cresswell-Smith, Naim Fanaj, Andia Meksi, Doireann Ni Dhalaigh, Hanna Reich, Victoria Ross, Sarita Sanches, Katherine Thomson, Chantal Van Audenhove, Victor Perez, Ella Arensman, Gyorgy Purebl en Benedikt L Amann
BACKGROUND: To improve the management of childhood urinary tract infections, it is essential to understand the incidence rates, testing and treatment strategy. METHODS: A retrospective study using data from 45 to 104 general practices (2000 to 202...
Auteurs:Hanne A Boon, Thomas Struyf, Jonas Crevecoeur, Nicolas Delvaux, Gijs Van Pottelbergh, Bert Vaes, Ann Van den Bruel en Jan Y Verbakel
