An elderly Belgian population group anno 1986 consisting of 53 men and 110 women above the age of 75 years with a mean age of 80 and 81 years, respectively, is characterized by relative obesity and low diastolic blood pressure, both in men and wom...
Auteurs:Hugo Kesteloot, Jan Heyrman, J Geboers, Jan De Lepeleire en W Lissens
Samples of 37 fresh human ovarian tumor biopsies were screened to detect proto-oncogene amplification and ras mutations. Three samples showed c-K-ras2 amplification; none of the other oncogenes tested revealed any gene amplification. 5-, 25-, and ...
Auteurs:LJ VANTVEER, R HERMENS, LAM VANDENBERGBAKKER, NC CHENG, GJ FLEUREN, JL BOS, FJ CLETON en PI SCHRIER
In four independent transfection experiments performed with high molecular weight DNA isolated from a human ovarian carcinoma, oncogenic NIH3T3 cells contained an activated mas gene in the in vivo tumorigenicity assay. Varying from 1.8 to 3.5 kb u...
Auteurs:LJ VANTVEER, LAM VANDENBERGBAKKER, RPMG HERMENS, RL DEPREZ en PI SCHRIER
Clinical and epidemiological studies indicate that the risk for gastric cancer is increased in pernicious anaemia, atrophic gastritis, postgastrectomy stumps. Ménétrier's disease and gastric adenomatous polyps. Using histoautoradiography, cell mat...