Publicaties

Correctly addressing the questions of worried citizens with respect to possible clusters of cancer occurrence requires a risk communication strategy that is informed by a previously established analytical procedure. The aim of this study was to an...

OBJECTIVE: To assess the impact of a multifaceted implementation strategy aiming to improve GP adherence to a clinical guideline on dementia. DESIGN: Controlled before and after study using data records from regional laboratories. The guideline wa...

Results of a randomized controlled trial have suggested a protective effect of selenium against prostate cancer. Few other prospective studies have been conducted to confirm or refute this. The association between prostate cancer and baseline toen...

Our meta-analysis was aimed at providing a systematic review of the literature regarding the effect of energy restriction on spontaneous mammary tumors in mice and at providing a more precise pooled (summary) estimate of the risk of mammary tumors...

Purpose of review: Expressed emotion refers to the amount of critical comments, hostility or emotional overinvolvement of a caregiver towards clients with severe and enduring psychiatric disorders. In family members, it is a well-established measu...

Aims/hypothesis: Several case-control studies have examined the association between the Gly792Arg variant in the IRS-1 gene and Type 2 diabetes, but most had limited power and results could therefore ve conflicting. Methods:We systematically revie...

We present a systematic review of prospective cohort studies. Our aim was to assess prognostic factors associated with functional recovery of patients with whiplash injuries. The failure of some patients to recover following whiplash injury has be...

OBJECTIVE: To compare the pharmacokinetics of two dosing regimens of cisapride and their effects on QT(c) interval. DESIGN: Thirty-one pre-term infants were enrolled in two neonatal intensive care units. In 16 infants, cisapride was started at 0.2...

Although case histories of depression preceding Parkinson's disease (PD) point to a possible pathophysiological relationship between these two disorders, there is as yet no epidemiological evidence to support this view. We compared the incidence o...

BACKGROUND: Although narrative reviews have concluded that there is strong support for familial clustering of prostate carcinoma, the association has never systematically been quantified in reviews. The purpose of this meta-analysis was to summari...

This study investigates the validity of retrospective determination of chorion type by asking the question to the mother about the number of placentas. In the "East Flanders Prospective Twin Survey" (EFPTS), accurate information on the placentatio...

Many guidelines for the management of low back pain in primary care have been published during recent years, but guidelines for physiotherapy do not yet exist. Therefore, physiotherapy guidelines have been developed, reflecting the consequences of...

Major risk factors for developing prostate cancer, including positive family history and African-American ethnicity, can be quantified for genetic counseling. Factors increasing familial risk for prostate cancer are closer degree of kinship, numbe...

Aim: There is a growing evidence that depression is associated with an increased mortality risk, but results from studies are ambiguous. To investigate whether depression leads to increased mortality, we reviewed the literature on depression and t...

Dit onderzoek vergeleek comorbiditeitsgegevens van dementerenden met die van niet-dementerenden en ging na of er qua comorbiditeit een verschil bestaat tussen een geïnstitutionaliseerde populatie en een huisartsenpraktijkpopulatie. Urine-incontine...

Ethical dilemmas in community mental health care is the focus of this article. The dilemmas are derived from a discussion of the results of a qualitative research project that took place in five countries of the European Union. The different stake...

De best mogelijke zorg komt tot stand door onderzoeksresultaten te combineren met de klinische expertise van de zorgverlener en de voorkeur van de patiënt. deze ruimere definitie van evidence based medicine biedt de verpleegkunde ruimte voor het o...